diff --git a/mingw-w64-opencolorio/0003-fix-python-sitearch.patch b/mingw-w64-opencolorio/0003-fix-python-sitearch.patch
new file mode 100644
index 0000000000..44ab380a52
--- /dev/null
+++ b/mingw-w64-opencolorio/0003-fix-python-sitearch.patch
@@ -0,0 +1,11 @@
+--- OpenColorIO-2.2.0/src/bindings/python/CMakeLists.txt.orig	2022-10-31 23:27:35.000000000 +0100
++++ OpenColorIO-2.2.0/src/bindings/python/CMakeLists.txt	2022-11-10 14:15:28.555728000 +0100
+@@ -227,7 +227,7 @@
+ 		PY_VERSION_PATCH=${Python_VERSION_PATCH}
+ )
+ 
+-if(WIN32)
++if(WIN32 AND NOT MINGW)
+     set(_Python_VARIANT_PATH "${CMAKE_INSTALL_LIBDIR}/site-packages")
+ else()
+     set(_Python_VARIANT_PATH "${CMAKE_INSTALL_LIBDIR}/python${Python_VERSION_MAJOR}.${Python_VERSION_MINOR}/site-packages")
diff --git a/mingw-w64-opencolorio/PKGBUILD b/mingw-w64-opencolorio/PKGBUILD
index eb4f3d05b0..c9138b8c4f 100644
--- a/mingw-w64-opencolorio/PKGBUILD
+++ b/mingw-w64-opencolorio/PKGBUILD
@@ -6,33 +6,37 @@ pkgname="${MINGW_PACKAGE_PREFIX}-${_realname}"
 conflicts=("${MINGW_PACKAGE_PREFIX}-${_realname}-git")
 replaces=("${MINGW_PACKAGE_PREFIX}-${_realname}-git")
 pkgver=2.2.0
-pkgrel=1
+pkgrel=2
 pkgdesc="A color management framework for visual effects and animation (mingw-w64)"
 arch=('any')
 mingw_arch=('mingw32' 'mingw64' 'ucrt64' 'clang64' 'clang32')
 url="https://opencolorio.org/"
 license=('spdx:BSD-3-Clause')
-depends=("${MINGW_PACKAGE_PREFIX}-boost"
-         "${MINGW_PACKAGE_PREFIX}-expat"
+depends=("${MINGW_PACKAGE_PREFIX}-expat"
          "${MINGW_PACKAGE_PREFIX}-freeglut"
+         "${MINGW_PACKAGE_PREFIX}-gcc-libs"
          "${MINGW_PACKAGE_PREFIX}-glew"
          "${MINGW_PACKAGE_PREFIX}-imath"
-         "${MINGW_PACKAGE_PREFIX}-libwinpthread-git"
          "${MINGW_PACKAGE_PREFIX}-lcms2"
-         "${MINGW_PACKAGE_PREFIX}-python"
+         "${MINGW_PACKAGE_PREFIX}-openexr"
          "${MINGW_PACKAGE_PREFIX}-yaml-cpp")
 makedepends=("${MINGW_PACKAGE_PREFIX}-cc"
              "${MINGW_PACKAGE_PREFIX}-cmake"
              "${MINGW_PACKAGE_PREFIX}-ninja"
              "${MINGW_PACKAGE_PREFIX}-pkg-config"
+             "${MINGW_PACKAGE_PREFIX}-pybind11"
              "${MINGW_PACKAGE_PREFIX}-pystring"
+             "${MINGW_PACKAGE_PREFIX}-python"
              "${MINGW_PACKAGE_PREFIX}-openimageio"
              "${MINGW_PACKAGE_PREFIX}-openshadinglanguage"
              "${MINGW_PACKAGE_PREFIX}-zlib")
+optdepends=("${MINGW_PACKAGE_PREFIX}-python: Python bindings")
 source=(${_realname}-${pkgver}.tar.gz::https://github.com/imageworks/OpenColorIO/archive/v${pkgver}.tar.gz
-        0002-install-pc.patch)
+        0002-install-pc.patch
+        0003-fix-python-sitearch.patch)
 sha256sums=('81e3b6e0e432d20347b6396c376f9fbeceac31c2cbefe2882d83112a5b0a8123'
-            'ba79929436bfffb0710335e43197b7c730089e2d9213f60c22416584dbcf2a4a')
+            'ba79929436bfffb0710335e43197b7c730089e2d9213f60c22416584dbcf2a4a'
+            '73660c114f5adfd6c089d0e91ae776601734e8b1ad4f6e773867d7eee4a1a5fb')
 
 apply_patch_with_msg() {
   for _patch in "$@"
@@ -45,7 +49,8 @@ apply_patch_with_msg() {
 prepare() {
   cd ${_realname}-${pkgver}
   apply_patch_with_msg \
-    0002-install-pc.patch
+    0002-install-pc.patch \
+    0003-fix-python-sitearch.patch
 }
 
 build() {
@@ -67,6 +72,7 @@ build() {
     -DCMAKE_CXX_STANDARD=14 \
     -DOCIO_BUILD_TESTS=OFF \
     -DOCIO_BUILD_GPU_TESTS=OFF \
+    -DPython_EXECUTABLE=${MINGW_PREFIX}/bin/python.exe \
     ../${_realname}-${pkgver}
 
   "${MINGW_PREFIX}"/bin/cmake.exe --build .