diff -Naur a/Lib/ctypes/__init__.py b/Lib/ctypes/__init__.py
--- a/Lib/ctypes/__init__.py	2014-03-09 12:40:08.000000000 +0400
+++ b/Lib/ctypes/__init__.py	2014-03-17 10:47:09.278800000 +0400
@@ -433,7 +433,9 @@
 cdll = LibraryLoader(CDLL)
 pydll = LibraryLoader(PyDLL)
 
-if _os.name in ("nt", "ce"):
+if _os.name == "nt" and _sys.version.find('GCC') >= 0:
+    pythonapi = PyDLL("libpython%d.%d%s.dll" % (_sys.version_info[:2] + (_sys.abiflags,)), None)
+elif _os.name in ("nt", "ce"):
     pythonapi = PyDLL("python dll", None, _sys.dllhandle)
 elif _sys.platform == "cygwin":
     pythonapi = PyDLL("libpython%d.%d.dll" % _sys.version_info[:2])