diff --git a/setup.py b/setup.py
index 049771d..619588c 100644
--- a/setup.py
+++ b/setup.py
@@ -30,6 +30,7 @@
 from subprocess import PIPE, CalledProcessError, Popen, check_call
 from sysconfig import get_config_var
 from traceback import print_exc
+from sysconfig import _POSIX_BUILD
 
 from packaging.version import Version as V
 from setuptools import Command, setup
@@ -152,7 +153,7 @@
     # is this necessary?
     if sys.platform.startswith('freebsd'):
         settings['libraries'].append('pthread')
-    elif sys.platform.startswith('win'):
+    elif sys.platform.startswith('win') and not _POSIX_BUILD:
         # link against libzmq in build dir:
         if sys.version_info < (3, 9, 2):
             # bpo-39825: EXT_SUFFIX is wrong from sysconfig prior to 3.9.2 / 3.8.7
@@ -513,7 +514,7 @@
             )
             line()
 
-        if sys.platform.startswith('win'):
+        if sys.platform.startswith('win') and not _POSIX_BUILD:
             # fetch libzmq.dll into local dir
             local_dll = localpath('zmq', libzmq_name + '.dll')
             if not zmq_prefix and not os.path.exists(local_dll):
@@ -609,7 +610,7 @@
             libzmq.define_macros.append(('ZMQ_IOTHREADS_USE_POLL', 1))
             libzmq.define_macros.append(('ZMQ_POLL_BASED_ON_POLL', 1))
 
-        if sys.platform.startswith('win'):
+        if sys.platform.startswith('win') and not _POSIX_BUILD:
             # include defines from zeromq msvc project:
             libzmq.define_macros.append(('FD_SETSIZE', 16384))
             libzmq.define_macros.append(('DLL_EXPORT', 1))