diff -urN ccache-3.3.2.orig/ccache.h ccache-3.3.2/ccache.h
--- ccache-3.3.2.orig/ccache.h	2016-09-29 04:44:46.000000000 +0800
+++ ccache-3.3.2/ccache.h	2016-10-23 19:01:12.582863400 +0800
@@ -258,7 +258,7 @@
 #endif
 
 // mkstemp() on some versions of cygwin don't handle binary files, so override.
-#ifdef __CYGWIN__
+#if defined(__CYGWIN__) && !defined(__MSYS__)
 #undef HAVE_MKSTEMP
 #endif
 
diff -urN ccache-3.3.2.orig/lockfile.c ccache-3.3.2/lockfile.c
--- ccache-3.3.2.orig/lockfile.c	2016-09-29 04:44:46.000000000 +0800
+++ ccache-3.3.2/lockfile.c	2016-10-23 19:01:26.574809400 +0800
@@ -40,7 +40,7 @@
 		free(my_content);
 		my_content = format("%s:%d:%d", hostname, (int)getpid(), (int)time(NULL));
 
-#ifdef _WIN32
+#if defined(_WIN32) || defined(__MSYS__)
 		int fd = open(lockfile, O_WRONLY|O_CREAT|O_EXCL|O_BINARY, 0666);
 		if (fd == -1) {
 			int saved_errno = errno;